17:00Registration 
18:00Opening reception ( food&drinks )
UMCU
When you arrive at the main entrance of the UMCU (hospital) follow the signs “MRSworkshop” to get to the registration and reception.
Optional guided tour to META-scan (20 min)
21:00Closing

8:30 Welcome, Introduction   
Session 1 – Basics of MRS
Moderators: Jannie Wijnen | Ralf Mekle
8:45Historical and Clinical overview of MRS
Arend Heerschap, PhD, Radboud University Medical Centre, Nijmegen, the Netherlands
9:15Basics of MRS, SVS, neurochemical profile
Uzay Emir, PhD, Purdue University, West Lafayette, USA
9:45SVS spectral editing
Robin de Graaf, PhD, Yale School of Medicine, New Haven, USA
10:15Artefacts and Correction (B0, B1, motion)
Christoph Juchem, PhD, Columbia University, New York, USA
10:45Break
Session 2 – MRSI / fast metabolic imaging techniques
Moderators: Peter Barker | Fan Lam
11:15 Basics of MRSI
Michal Povazan, PhD, Johns Hopkins Medical Institutions, Baltimore, USA
11:45 Accelerated MRSI and reconstruction
Bernard Strasser, PhD, Martinos Centre, Boston, USA
12:15Consensus discussion MRSI
Andrew Maudsley, PhD, University of Miami, Miami, USA
13:00Lunch Break
Session 3 – Quality of MRS/MRSI
Moderators: Gulin Oz | Anke Henning
Parallel session 1
14:00 Quality of MRS/MRSI
Ivan Tkac, PhD, CMRR University of Minnesota, Minneapolis, USA
Practical at 7T MR scanner
Deuterium Metabolic Imaging
Practical at In-vivo NMR-lab
Preferred papers presentations
Moderators: Gulin Oz | Anke Henning
14:30 Cycled water-suppression single voxel spectroscopy in cardiac 1H MRS
Belinda Ding, University of Oxford, Oxford, UK
MRS quantification software
MIDAS by Andrew Maudsley
14:45 Full Brain High Resolution 3D-MRSI at 7 Tesla within 30 Minutes via 3D-CONCEPT
Philipp Moser, High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Austria
15:00 Whole Brain High Resolution Metabolite Mapping Using 1H FID MRSI with Dynamic B0 Shimming at 9.4T
Sahar Nassirpour, Max Planck Institue for Biological Cybernetics, Tuebingen, Germany
15:15 Density-Weighted Concentric Ring Trajectory using simultaneous multi-slice (SMS) acceleration: 3D Metabolite-cycled Magnetic Resonance Spectroscopy Imaging at 3 T
Uzay Emir, Purdue University, West Lafayette, USA
15:30Break BreakBreakBreak
16:00 Poster session 1
16:30 Practical at 7T MR scanner
Deuterium Metabolic Imaging
MRS quantification software
INSPECTOR by Christoph Juchem
17:30 -18:00 Consensus discussion MRS quality
Roland Kreis, PhD, University and Inselspital Bern, Bern, Switzerland
19:00 Conference Dinner (location railway museum)

Session 4 – Spectral Fitting and Quantitation
Moderators: Cristina Cudalbu | Nuno Barros
Parallel session 2
8:30 Preprocessing
Jamie Near, PhD, McGill University, Montreal, Canada
Practical at 7T MR scanner
Body MRS, MULTIX
8:50 Parametric fitting
Brian Soher, PhD, Duke University School of Medicine, Durham, USA
9:10 Machine learning
Diana Sima, PhD, University of Leuven, Leuven, Belgium
Preferred papers presentations
Moderators: Cristina Cudalbu | Nuno Barros
9:30 Simultaneous fitting of the individual spectra recorded by multichannel receive arrays in 1H MRS investigations of global brain pathology
Maike Hoefemann, Departments of Radiology and Biomedical Research, University of Bern, Bern, Switserland
9:45 Reliability of Quantifying Small Resonances in Single Voxel Short Echo Time Human Brain MRS: Concentrations Measured at 3 T and 7 T
Mellissa Terpstra, University of Minnesota, Minneapolis, USA
10:00 How do voxel size and shape in whole-brain MRSI affect spectral quality? A simulation study on 1.5T, 3T, 7T and 9.4T
Stanislav Motyka, High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria
10:15 Spectral fitting challenge results (update from 2016) + consensus discussion
Gosia Marjanska, PhD, CMRR University of Minnesota, Minneapolis, USA
10:45 BreakBreakBreakBreak
Session 5 – Applications MRS
Moderators: Alexander Lin | Joseph Cousins
11:15 Clinical applications
Petra Pouwels, PhD, Amsterdam UMC, Amsterdam the Netherlands
Practical at 7T MR scanner
31P MRSI
MRS quantification software
FID-A by Jamie Near
11:35Pre-clinical application
Jeanine Prompers, PhD, University Medical Centre Utrecht, Utrecht, the Netherlands
11:55 Clinical applications for Cancer
Ovidiu Andronesi, PhD, Martinos Centre, Boston, USA
Preferred papers presentations
Moderators: Alexander Lin | Joseph Cousins
12:15 Deletion of CRTC1 is associated with strong neuroenergetic dysfunctions in a mouse model of mood disorders.
Antoine Cherix, Laboratory for Functional and Metabolic Imaging (LIFMET), Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
MRS quantification software
VESPA by Brian Soher
12:30 In vivo longitudinal 1H MRS Study of hippocampal, cerebral and striatal metabolic changes in BDL rats
Dunja Simicic, LIFMET, CIBM, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
12:45 The utility of ultra-high resolution MRSI on detectability of neurochemical changes in multiple sclerosis-related brain lesions
Eva Heckova, High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University in Vienna, Vienna, Austria
13:00 Early and profound neurometabolic changes in pup rat with cholestatic liver disease compared to changes in adult rats, 1H MRS study
Veronika Rackayova, LIFMET, CIBM, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
13:15Lunch BreakLunch BreakLunch BreakLunch Break
Session 6 – MRS outside the brain
Moderators: Chris Rodgers | Eva Ratai
Parallel session 3
14:00 Technical challenges of body MRS
Martin Meyerspeer, PhD, Medical University of Vienna, Vienna, Austria
Practical at 7T MR scanner
Brain / shimming hardware
Practical at In-vivo NMR-labMRS quantification software
JMRUI by Zenon Starcuk
14:20Cardiac MRS
Ladislav Valkovic, PhD, University of Oxford, Oxford, UK
14:40 Muscle and Liver
Martin Krssak, PhD, MedUni Vienna, Vienna, Austria
15:00 Breast and Prostate
Tom Scheenen, Radboud University Medical Centre, Nijmegen, the Netherlands
MRS quantification software
spectrIM by Nuno Barros
Preferred papers presentations
Moderators: Chris Rodgers | Eva Ratai
15:20 Assessment of perfused ex vivo human livers by MRS and MRI
Liam Young, OCMR, University of Oxford, Oxford, UK
15:35Sexual dimorphism and maturation effects in skeletal muscle metabolites: a proton MRS study
Lievens Eline, Ghent University, Ghent, Belgium
15:50 Myocardial metabolism in amyloidosis quantified by proton MR spectroscopy
Mareike Gastl, Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland
16:05BreakBreakBreakBreak
16:30Poster session 2
Session 7 – Multinuclear MRS/MRI
Moderators: Wolfgang Bogner | Chloe Najac
17:30 Multi nuclear MRS/MRSI Technical
Pierre-Gilles Henry, PhD, CMRR University of Minnesota, Minneapolis, USA
17:50 Multi nuclear MRS/MRSI Applications
Fei Du, PhD, Harvard University, Boston, USA
19:00 Conference Dinner (location on campus)

Session 8 – MRS in neuroscience and emerging technologies
Moderators: Ben Babourina-Brooks | Rolf Gruetter
8:30DWS
Itamar Ronen, PhD, Leiden University Medical Centre, Leiden, the Netherlands
8:50fMRS
Peter Morris, PhD, University of Nottingham, Nottingham, UK
9:10PET and MRS
Bernard Lanz, PhD, University of Nottingham, Nottingham, UK
LIFMET, CIBM, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
Proferred papers presentations
Moderators: Ben Babourina-Brooks | Rolf Gruetter
9:30Integrated Imaging of [11C]-PBR28 PET, MR Diffusion and Magnetic Resonance Spectroscopy in Amyotrophic Lateral Sclerosis
Eva-Maria Ratai, Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, USA
9:45Deuterium Metabolic Imaging (DMI), a novel method for in vivo mapping of glucose metabolism in brain and liver
Henk De Feyter, Yale University, New Haven, USA
10:00In-vivo 1H MRS and ex-vivo ESR spectroscopy of Oxidative Stress in a rat model of Chronic Hepatic Encephalopathy
Katarzyna Pierzchala, LIFMET, CIBM, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
10:15Both oxygen supply and phosphocreatine recovery rate show proximo-distal gradients along the human tibialis anterior after exercise
Linda Heskamp, Department of Radiology, Radboud University Medical Center, Nijmegen, Netherlands
10:30Break
11:00MRS and the Physiome project
In silico models seeking in vivo numbers.
Jeroen Jeneson, PhD, University of Groningen, Groningen, the Netherlands
Session 9 – Consensus Discussion
Moderator: Veronika Rackayová
11:30 NMR in biomedicine special issue on Consensus in MRS
In-Young Choi, PhD, University of Kansas Medical Centre, Kansas City, USA
13:00 Closing Remarks – Adjourn

NOTE to the parallel sessions:

Parallel Program Sign-up

We will be running several parallel sessions (tour of animal facility, 2H MRS, hardware and software demos) during the regular workshop program. If you wish to attend one of these sessions it is very important that you sign up as space is limited. During registration we will have a sign-up sheet where you can fill in your name under the session that you would like to attend. Since space is limited, spots will be allocated on a first come first serve basis.

MRS software demonstrations will be scheduled in the parallel sessions. The order of presentation of the software package is tentatively assigned and might be changed in the coming months.
Software packages that will be presented during the workshop are:
INSPECTOR – Christoph Juchem
Vespa – Brian Soher
FID-A – Jamie Near
SpectrIM – Nuno Barros
JMRUI – Zenon Starčuk
MIDAS – Andrew Maudsley